Presence of Mind Rune League of Legends 2025

Damaging an enemy champion increases your mana/energy regeneration by 6 - 50 (melee) / 4.8 - 40 (ranged) (based on level) mana or 6 energy instantly, 8 second cooldown
Takedowns restore 15% of your maximum mana or energy.
Other runes
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Triumph
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Sudden Impact
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Resolve
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Zombie Ward
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Conqueror
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Cosmic Insight
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Press the Attack
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Biscuit Delivery
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Overheal
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Magical Footwear
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Unsealed Spellbook
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Hextech Flashtraption
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Electrocute
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Demolish
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Revitalize
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Grisly Mementos
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Predator
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Second Wind
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Conditioning
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Nimbus Cloak
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Last Stand
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Inspiration
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Glacial Augment
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Bone Plating
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Deep Ward
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Axiom Acanist
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Minion Dematerializer
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Hail of Blades
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Waterwalking
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Fleet Footwork
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Summon Aery
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Legend: Bloodline
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Transcendence
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Phase Rush
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First Strike
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Ingenious Hunter