First Strike Rune League of Legends 2025
Attacks or abilities against an enemy champion within 0.25s of entering champion combat grants 10 (+4% damage dealt) gold and First Strike for 3 seconds, causing you to deal 7% extra damage against champions, and granting 100% (70% for ranged champions) of bonus damage dealt as gold.
Cooldown: 25 - 15s
Other runes
-
Axiom Acanist
-
Last Stand
-
Relentless Hunter
-
Manaflow Band
-
Press the Attack
-
Scorch
-
Grasp of the Undying
-
Unflinching
-
Coup de Grace
-
Magical Footwear
-
Unsealed Spellbook
-
Revitalize
-
Sorcery
-
Zombie Ward
-
Time Warp Tonic
-
Demolish
-
Cheap Shot
-
Summon Aery
-
Second Wind
-
Ingenious Hunter
-
Domination
-
Electrocute
-
Conqueror
-
Lethal Tempo
-
Eyeball Collection
-
Absolute Focus
-
Approach Velocity
-
Arcane Comet
-
Shield Bash
-
Conditioning
-
Dark Harvest
-
Precision
-
Deep Ward
-
Triumph
-
Biscuit Delivery
-
Legend: Alacrity
