First Strike Rune League of Legends 2025
Attacks or abilities against an enemy champion within 0.25s of entering champion combat grants 10 (+4% damage dealt) gold and First Strike for 3 seconds, causing you to deal 7% extra damage against champions, and granting 100% (70% for ranged champions) of bonus damage dealt as gold.
Cooldown: 25 - 15s
Other runes
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Unflinching
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Summon Aery
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Axiom Acanist
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Cash Back
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Relentless Hunter
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Aftershock
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Gathering Storm
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Cosmic Insight
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Shield Bash
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Second Wind
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Nimbus Cloak
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Triumph
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Resolve
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Ghost Poro
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Electrocute
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Inspiration
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Nullifying Orb
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Legend: Alacrity
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Celerity
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Scorch
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Dark Harvest
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Conditioning
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Conqueror
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Bone Plating
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Hail of Blades
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Sudden Impact
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Legend: Haste
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Approach Velocity
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Magical Footwear
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Ultimate Hunter
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Phase Rush
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Sixth Sense
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Unsealed Spellbook
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Coup de Grace
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Sorcery
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Fleet Footwork
