First Strike Rune League of Legends 2025
Attacks or abilities against an enemy champion within 0.25s of entering champion combat grants 10 (+4% damage dealt) gold and First Strike for 3 seconds, causing you to deal 7% extra damage against champions, and granting 100% (70% for ranged champions) of bonus damage dealt as gold.
Cooldown: 25 - 15s
Other runes
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Deep Ward
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Electrocute
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Bone Plating
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Guardian
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Revitalize
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Cosmic Insight
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Nullifying Orb
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Dark Harvest
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Ghost Poro
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Legend: Haste
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Absolute Focus
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Glacial Augment
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Predator
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Overheal
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Approach Velocity
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Legend: Alacrity
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Jack of All Trades
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Legend: Bloodline
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Nimbus Cloak
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Magical Footwear
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Last Stand
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Grisly Mementos
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Ravenous Hunter
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Coup de Grace
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Font of Life
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Triumph
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Cut Down
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Overgrowth
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Press the Attack
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Minion Dematerializer
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Press the Attack
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Triple Tonic
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Sorcery
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Grasp of the Undying
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Zombie Ward
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Demolish
