First Strike Rune League of Legends 2025
Attacks or abilities against an enemy champion within 0.25s of entering champion combat grants 10 (+4% damage dealt) gold and First Strike for 3 seconds, causing you to deal 7% extra damage against champions, and granting 100% (70% for ranged champions) of bonus damage dealt as gold.
Cooldown: 25 - 15s
Other runes
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Second Wind
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Cosmic Insight
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Legend: Alacrity
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Press the Attack
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Aftershock
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Triple Tonic
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Sixth Sense
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Eyeball Collection
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Transcendence
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Electrocute
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Phase Rush
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Absolute Focus
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Nullifying Orb
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Gathering Storm
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Ultimate Hunter
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Hextech Flashtraption
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Deep Ward
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Arcane Comet
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Waterwalking
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Perfect Timing
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Fleet Footwork
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Absorb Life
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Revitalize
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Legend: Tenacity
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Ingenious Hunter
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Sudden Impact
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Summon Aery
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Electrocute
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Lethal Tempo
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Inspiration
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Cash Back
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Unflinching
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Bone Plating
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Legend: Haste
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Shield Bash
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Domination
