First Strike Rune League of Legends 2025
Attacks or abilities against an enemy champion within 0.25s of entering champion combat grants 10 (+4% damage dealt) gold and First Strike for 3 seconds, causing you to deal 7% extra damage against champions, and granting 100% (70% for ranged champions) of bonus damage dealt as gold.
Cooldown: 25 - 15s
Other runes
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Bone Plating
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Cheap Shot
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Overheal
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Magical Footwear
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Eyeball Collection
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Coup de Grace
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Axiom Acanist
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Gathering Storm
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Font of Life
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Manaflow Band
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Ghost Poro
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Future's Market
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Unsealed Spellbook
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Time Warp Tonic
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Ultimate Hunter
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Press the Attack
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Phase Rush
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Predator
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Electrocute
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Deep Ward
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Zombie Ward
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Nullifying Orb
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Cut Down
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Grisly Mementos
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Glacial Augment
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Sixth Sense
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Legend: Alacrity
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Sudden Impact
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Demolish
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Domination
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Legend: Haste
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Electrocute
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Celerity
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Fleet Footwork
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Hextech Flashtraption
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Cash Back
