First Strike Rune League of Legends 2025
Attacks or abilities against an enemy champion within 0.25s of entering champion combat grants 10 (+4% damage dealt) gold and First Strike for 3 seconds, causing you to deal 7% extra damage against champions, and granting 100% (70% for ranged champions) of bonus damage dealt as gold.
Cooldown: 25 - 15s
Other runes
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Unflinching
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Presence of Mind
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Ravenous Hunter
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Electrocute
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Legend: Tenacity
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Shield Bash
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Electrocute
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Ultimate Hunter
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Sudden Impact
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Axiom Acanist
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Bone Plating
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Relentless Hunter
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Nullifying Orb
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Manaflow Band
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Gathering Storm
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Perfect Timing
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Waterwalking
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Ingenious Hunter
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Precision
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Last Stand
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Glacial Augment
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Fleet Footwork
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Minion Dematerializer
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Lethal Tempo
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Overgrowth
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Absorb Life
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Dark Harvest
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Ghost Poro
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Arcane Comet
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Guardian
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Overheal
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Cosmic Insight
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Magical Footwear
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Nimbus Cloak
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Predator
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Cash Back
